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Celebrating 25 years of FISH probe development, OGT announce further expansion to the comprehensive Cytocell Aquarius^® Haematology range

Oxford, UK – 11 October 2016. Oxford Gene Technology (OGT), The Molecular Genetics Company, has today announced a significant expansion of its existing catalogue of Cytocell Aquarius^® Haematology probes for fluorescence in situ hybridisation (FISH) — underlining the company's position as the one-stop-shop for high-quality FISH probes. These additions have been introduced due to an ongoing commitment to use customer input as a major driver for the rapid development of the latest research-relevant probes. The 14 newly launched probes are:

 ♦ CBFB Proximal Probe Red

 ♦ CBFB Distal Probe Green

 ♦ MECOM Probe Red

 ♦ RUNX1 Probe Green

 ♦ NUP98 Proximal Probe Red

 ♦ NUP98 Distal Probe Green

 ♦ TET2 Probe Red

 ♦ USP46 (4q12) Probe Green

 ♦ CSF1R/RPS14 (5q32-q33) Probe Red

 ♦ EGR1/CDC25C (5q31) Probe Green

 ♦ TERT (5p15.33) Probe Aqua

 ♦ CUX1 (7q22) Probe Green

 ♦ EZH2 (7q36) Probe Red

 ♦ Chromosome 7 Alpha Satellite Probe Aqua

The new cost-effective and quality-assured probes are optimised for use on common sample types and are sold as pre-mixed, easy-to-use formulations to minimise experimental errors. The importance of researchers’ input in today’s announcement demonstrates the ongoing success of OGT’s myProbes^® service, which enables scientists to order custom-made probes for virtually any sequence in the human genome. All probes are produced under GMP/GLP guidelines using the Cytocell BAC-2-FISH™ process, combining high-intensity signals with low levels of background fluorescence and providing maximum confidence in results.

As the longest-standing FISH probe manufacturer in the world, 2016 marks 25 years of Cytocell expertise and customer service in the development and production of FISH products. “myProbes gives us the opportunity to get continuous input from our customers,” explains Faidra Partheniou, Haematology Product Manager at OGT, “it truly helps us to respond quickly to changes in customer demand and it helps researchers by providing a first port of call for rapid development of new probes. These latest additions to our Cytocell Aquarius portfolio are testament to this.”

OGT also offers the opportunity to evaluate the accurate, user-friendly FISH probes in customer’s own labs free of charge by simply requesting up to four free probes from their extensive range.

To find out more about the comprehensive range of Cytocell FISH probes and to request a free sample, please visit www.cytocell.com . You can also find out more at booth #1230 at the annual meeting of the American Society of Human Genetics (ASHG) in Montreal from 18 to 22 October.

The new additions to the Cytocell Aquarius^® Haematology probe range are currently only available within North America as analyte specific 黄金城游戏 (ASRs), analytical and performance characteristics are not established. CE-marked IVD versions for sale in Europe are anticipated.

For further information, please contact:

Oxford Gene Technology, Begbroke Science Park, Begbroke Hill, Woodstock Road, Begbroke, Oxfordshire, OX5 1PF, U.K.

T: +44 (0) 1865 856826 ; F: +44 (0) 1865 848684

E: [email protected] ;      W: www.ogt.com ;          Twitter: @OxfordGeneTech

About Oxford Gene Technology

Oxford Gene Technology (OGT) provides world-class genetics research solutions to leading clinical and academic research institutions. Founded by Professor Sir Edwin Southern, and with customers in over 60 countries worldwide, OGT has a strong reputation and increasing share in the large and growing genomic medicine market. The Company’s Cytocell^®, CytoSure™ and SureSeq™ range of fluorescence in situ hybridisation (FISH), microarray and next generation sequencing (NGS) products deliver high-quality genetic analysis, enabling accurate identification and confirmation of the causative variation underlying genetic disease.

For more information on the Company, please visit our website at www.ogt.com

CytoSure™, SureSeq™ and myProbes^®: For Research Use Only; Not for Use in Diagnostic Procedures. myProbes^®: Analyte Specific Reagent. Analytical performance characteristics are not established. Cytocell: Some products may not be available in the US.